Is it possible to develop coronavirus vaccine in 18 months?

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As a young researcher in the late 1980s, Michael Kinch wanted to solve the biggest medical puzzle of the day: how to design an HIV vaccine. But dozens of well-funded labs were attacking the problem, a solution seemed easily within reach, and Kinch moved on.

More than 30 years and 30 million deaths later, there’s still no approved HIV vaccine -- a cautionary tale for anyone expecting a coronavirus vaccine within the next year, according to Kinch, a former drug developer who’s now associate vice chancellor at Washington University in St. Louis.

“There’s a built-in assumption that there will be a vaccine,” Kinch said. “We just have to go into it very sober.”
As worldwide cases surge past 750,000, governments, investors and the public are keenly watching the breakneck race to deliver coronavirus vaccines that could prevent future infections. Researchers are seen as the saviors who will deliver therapies and vaccines needed to defeat the coronavirus, and President Donald Trump has urged drugmakers to “get it done.”

Among the majority of the public, vaccines are embraced as safe and straightforward: show the virus or a key piece of it to the immune system to remember so that it’s ready when a real infection occurs. They’re typically far cheaper than drugs and can offer protection for decades, virtually for life.

But getting there is far from easy. Most vaccines go through years of tests before they hit the market; 12 to 18 months would be extraordinarily fast. The coronavirus shots moving most rapidly are made with brand-new technologies that have never proven useful in humans.
Why Coronavirus Drugs, Vaccine Require More Time: QuickTake

Even vaccines based on tried-and-true methods often have side effects that would limit, or prohibit, their use. Sanofi’s dengue vaccine can worsen symptoms in some people who haven’t yet been infected, restricting use, and a vaccine against Lyme disease developed by SmithKline Beecham, now GlaxoSmithKline Plc, was pulled in 2002 amid concerns about links to arthritis.
The world’s foremost experts in the field have seen the perils of predicting the arrival of a vaccine. In 1984, then U.S. Health and Human Services Secretary Margaret Heckler said a shot to prevent HIV would be ready for testing within two years. Researchers have chased that goal ever since.

Vaccine specialists this time are turning to technology aimed at speeding up a process that has traditionally taken 10 years or more. National Institute of Allergy and Infectious Diseases Director Anthony Fauci and others have predicted a coronavirus vaccine could be ready in a year to 18 months. Dozens of companies and universities around the world are pursuing a vaccine, among them Sanofi, Johnson & Johnson and Moderna Inc.
One of the front-runners, backed by the U.S. institute, is the approach used by Moderna that involves adding viral genetic material to human cells, inducing them to make proteins that spur an immune response. The U.S. company said March 16 that it treated its first patient in an early study.
The novel method is largely untested, and Holden Thorp, editor in chief of the Science family of journals, points out there are no guarantees that such messenger RNA vaccines, and others like it, will achieve their ambitious targets. Falling short could cost both society and faith in science, he said.
Double-Time
The concern is “people would get their hopes up and think that we’re going to achieve something sooner than we are, which will be demoralizing if we aren’t able to do that,” Thorp said. “Long-term, I’m worried that if science is portrayed as not coming through fast enough, that could have lasting damage.”
While similar concerns apply to new drugs, test results from Gilead Sciences Inc.’s remdesivir, first aimed at Ebola, are due next month. Regeneron Pharmaceuticals Inc. said earlier this month its efforts to develop a drug are ahead of schedule and it could start testing in humans this summer.



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immortal2

Even if vaccine is developed it won't be available to general public in next 18-24 months,. Vaccine has to undergo many tests before it is available to general public.
Hope for the best.

Dev

Currently world doesn't have time. Lockdown is the only way now. Stopping the spread of corona is the only way currently.