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▼ Children who receive the measles, mumps and rubella (MMR) vaccine are not at increased risk for autism, and that includes children who are sometimes considered to be in "high risk" groups for the neurodevelopmental disorder, a massive new study finds.
The new study, published today (March 4) in the journal Annals of Internal Medicine, is one of the largest studies of its kind to date. In it, researchers looked at the records of more than 657,000 children born in Denmark between 1999 and 2010, including about 6,500 who had received an autism spectrum disorder(ASD) diagnosis. ASD is a neurodevelopmental condition that affects a person's ability to communicate, interact and behave appropriately with others in social situations.
The study shows, as many before it have time and again, that "[caregivers] shouldn't choose to not vaccinate because of this punitive association between the MMR [vaccine] and autism," said study principal investigator Anders Hviid, a senior researcher in the Department of Epidemiology Research at Statens Serum Institut in Copenhagen. "There's really strong science that there is no association."
The idea that the measles component of the MMR vaccine might be linked to autism began with a small, now-retracted 1998 study in the journal The Lancet. That research looked at 12 children with developmental delays, and eight of the kids had autism. It's since come to light that the lead researcher had several conflicts of interest: He had been paid by a law firm that wanted to sue the vaccine manufacturer, and he had a patent for a "safer" measles vaccine that he had developed before doing the 1998 study, according to a 2011 report in the journal The BMJ.
Since 1998, countless studies have found no link between the MMR vaccine and autism, including a large 2002 study in The New England Journal of Medicinethat Hviid carried out with his colleagues; that research looked at 537,000 children born in Denmark between 1991 and 1998. But after the publication of that study, Hviid heard from concerned parents and so-called anti-vaxxers who questioned whether "susceptible" children might be at risk for autism after receiving the MMR vaccine.undefined
"We saw an opportunity to re-examine the association in the same setting but with new children," Hviid told Live Science. "We also looked at how we could address some of the criticisms of our original study."
What they studied (▪ ▪ ▪)
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